Periodontitis is a common chronic inflammatory disease initiated by bacteria. This results in:
- bone resorption
- tooth loss, and
- systemic inflammation
One of the best Complementary and Alternative Medicine supplement for Gum Disease is DHA.A 2010 study from Japan showed that dental disease was1.5 times higher in people with low levels of DHA.
A recent 2014 study by Mukamal et al found that administering 2,000 mg per day of omega-3 fatty acid docosahexaenoic acid (DHA) with low-dose aspirin reduced periodontitis in humans.
Gingival crevicular fluid samples were analyzed for changes in:
- high-sensitivity C-reactive protein (hsCRP) and
- interleukins 6 and 1β (IL-6 and IL-1β)
DHA supplementation decreased mean pocket depth and gingival index; plaque index and bleeding on probing did not change.
However, further complementary medicine research studies are required to determine the mode of action and optimal aspirin concentration or alternative to aspirin. The proposed mechanism of action is that aspirin to produce resolvins and protectins; novel lipid mediators in anti-inflammation and resolution.
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