A 2015 Australian study conducted by researchers from the Cancer Council NSW found that women who use menopausal hormone therapy (MHT), have double the risk of developing breast cancer compared to women who never used MHT. In addition when women stop using MHT, the increased risk drops and becomes the same as with other women who don’t use it. The study, published in the International Journal of Cancer, conforms previous findings in the US and UK.
Professor Karen Canfell from the Cancer Council NSW commented, “The message to convey is that it’s important that women check in with their doctor every six months about the continuing use of MHT, because the risk of breast cancer increases as duration of use increases,” .
The researchers affirmed that HRT can still be advised for alleviating moderate to severe symptoms of menopause such as hot flushes and vaginal dryness. However, it is important to note that the risks are greater with use of combined oestrogen-progestagen as opposed to oestrogen-only therapy.
these findings will also encourage the increased use of bio-identical hormones. Bio-identical hormones are hormones synthesised to resemble identically, the natural hormones produced by the ovary. Pharmaceutical companies prefer to produce synthetic hormones (antagonist and agonist based), but these can cause various side effects due to a variety of physiological reasons.
If bio-identical hormones are the preferable mode of treatment then we need to consider the following:
- The physiological concentrations administered
- Pharmokinetics and pharmacological properties
- Do they have the same binding constants, up-regulation, down-regulation effects etc
- Is there a cascade effect post- administration that can be detrimental
- What do current observational studies show?
Possibly the best treatment option for menopause is an integrative healthcare solution of bio-identical hormones with Complementary and Alternative Medicine (CAM) therapies such as Ayurveda, TCM , Homeopathy and Lifeline Technique strategically implemented to deal with the physical and emotional aspects of menopause.